"talk to"和"talk with"在意思上非常相似，都表示与某人交谈或沟通。然而，它们之间存在一些细微的区别。
词组翻译区别：
talk to：与某人交谈
talk with：与某人交谈
单词形式区别：
talk to：动词短语，由动词"talk"和介词"to"组成
talk with：动词短语，由动词"talk"和介词"with"组成
词组短语搭配：
talk to someone：与某人交谈
talk to a group：向一群人讲话
talk with someone：与某人交谈
talk with a friend：与朋友交谈
talk with colleagues：与同事交谈
含义解释区别：
"talk to"强调的是单向的沟通，通常是指一个人向另一个人传达信息或表达观点。例如："I talked to my boss about my concerns."（我向我的老板表达了我的担忧。）
"talk with"则更强调双向的交流，通常是指两个人之间的对话或讨论。例如："I had a great conversation with my sister last night."（昨晚我和姐姐进行了一次很棒的对话。）
语法详解区别：
"talk to"后面通常跟一个宾语，表示与谁交谈。宾语可以是人、动物或物体。例如："She talked to the dog for hours."（她和狗谈了几个小时。）
"talk with"后面也可以跟一个宾语，表示与谁交谈。宾语通常是人。例如："He talked with his teacher about his grades."（他和他的老师谈论了他的成绩。）
句子：
I need to talk to you about something important.（我需要和你谈一件重要的事情。）
She talks to her plants every morning.（她每天早上都会和她的植物说话。）
Can we talk with each other more often?（我们能更经常地交流吗？）
He talked with his parents on the phone last night.（昨晚他通过电话和父母交谈。）
They talked with their advisor about their future plans.（他们和他们的导师谈论了他们的未来计划。）
首先我们来看下talk to sb、talk with sb的大致意思
talk to sb：词性为短语动词，talk to sb是指向某人说话或与某人交流。其中to是介词，表示目标。talk to sb强调的是发出信息的一方。
talk with sb：词性为短语动词，talk with sb也是指与某人说话或交流。with是介词，表示陪同、伴随。talk with sb强调的是双方的交流对话。
通过下面的图我们了解下talk to sb、talk with sb的含义、发音和用法
接下来我们讲解几个用例，希望这些用例可以加深您的理解
talk to sb：
I need to talk to the teacher.
(我需要去和老师交谈一下。)
He is talking to the client.
(他正在和客户交谈。)
She decided to talk to his parents.
(她决定与他父母好好谈谈。)
Please talk to me.
(请你和我说话。)
They are talking to experts about this issue.
(他们正在与专家讨论这个问题。)
I want to talk to you about this plan.
(我想与你谈谈这个计划。)
talk with sb：
I want to talk with you about this issue.
(我想和你交谈一下这个问题。)
They are talking with the senior management.
(他们正在与高层管理层进行会谈。)
Please talk with me about this plan.
(请你和我一起讨论这个计划。)
She likes to talk with her friends.
(她喜欢与朋友们畅所欲言。)
They are talking with each other while having coffee in the cafe.
(他们在咖啡馆里边喝咖啡边聊天。)
I hope to talk with the experts about this topic.
(我希望能与专家讨论一下这个课题。)