Recently, the generation of a novel transgenic mouse expressing Cre recombinase under the control of the mast cell protease 5 promotor has been reported.34Crossing of these mice with the recently generated iDTR mice35results in a mouse in which mast cells exclusively express a high affinity diphtheria toxin receptor.The subsequent application of diphtheria toxin then leads to the depletion of these cells. This conditional mast-cell-ablated mouse may allow analysis of the role of mast cells in disease models without affecting other immune cell subsets.
大概意思出来就行,语句通顺什么的我自己来弄。关键词语表错了,谢谢了~!
额,,,大概意思很混乱啊。。。直接机器翻译我灵格斯就完了……谢谢你们啊,麻烦了