【用 法】作主语、宾语、定语；指原则性的问题
英文解释
简明释义
major issues [matters] of principle；cardinal questions of right and wrong；cardinal [major] issues of right and wrong；(between) right and wrong on cardinal issues；
例句
教皇不再是地方上的一个新的大是大非的头大红帽，而是这顶帽子是梵蒂冈信使他在罗马的住所。
The pope no longer places the large red hat on the head of a new cardinal; instead, the hat is delivered to his residencein rome by a vatican messenger.
购买后允许这些可耻和暗示，我们发现其中的主教人数上诉人，一个大是大非，大约18岁，与3000神职人员。
After allowing for these shameful and suggestive purchases, we find among the number of the appellants, one cardinal,about eighteen bishops, and three thousand clerics.
我永远不会明白为什么任何公司会采取一个这些大是大非的旧电影，常常在拍摄65或70毫米，然后再转让，它甚至没有清理移交打印有时。
I'll never understand why any company would take one of these great old films, often filmed in 65 or 70mm and thentransfer it without even cleaning the transfer print sometimes.
而这些大是大非食用游戏鱼可以在这里找到这一年的大部分时间，他们宁愿寒冷的水中，使春季通常是最好的时候，今年这一要求后物种。
While these great eating game fish can be found here most of the year, they prefer colder water so spring is generallythe best time of year for this sought after species.
