talk to sb 和talk with sb的区别如下所示。
1. 释义区别：
talk to sb：向某人说话，表示单向的沟通，一方向另一方传递信息。
talk with sb：与某人交谈，表示双向的对话，双方互相交流信息。
例句：
Can I talk to you about a personal matter?（我能跟你谈谈个人问题吗？）
Let's talk with our team members and get their input.（我们与团队成员交流一下，听听他们的意见。）
2. 用法区别：
talk to sb：常用于一对一的沟通，或者一个人对多个人的沟通。
talk with sb：常用于双向交流或团体讨论。
例句：
The teacher talked to the student after class.（老师下课后和学生单独交谈。）
We need to talk with the whole team to make a decision.（我们需要与整个团队讨论，做出决策。）
3. 使用环境区别：
talk to sb：适用于较正式的场合，一方向另一方传递信息。
talk with sb：更通用，适用于正式或非正式的场合，双方进行交流。
例句：
He talked to the CEO about his career development.（他和首席执行官谈了谈他的职业发展。）
She talked with her friend about their weekend plans.（她和朋友讨论了周末的计划。）
4. 影响范围区别：
talk to sb：强调信息的传递，着重在单方面与某人交谈。
talk with sb：强调双向交流，重点在于与某人进行对话。
例句：
I need to talk to the manager to get more details.（我需要与经理交谈，以获取更多细节。）
Let's talk with our customers to understand their needs.（让我们与客户交流，了解他们的需求。）
5. 形象区别：
talk to sb：更倾向于指示或传达信息的行为。
talk with sb：更倾向于开放性的对话或交谈。
例句：
The doctor talked to the patient about their treatment options.（医生向患者介绍了他们的治疗选择。）
She enjoyed talking with her colleague at the office party.（她喜欢在办公室聚会时与同事交谈。）