although和despite的区别有：
1、语气强弱的区别
although的语气较重，despite相比较轻。
2、词性不同
although只能是从属连词，而despite可以作为介词和名词使用。
3、句中位置不同
although可置于句首(此时多用逗号与主句分开),也可置于句末(此时用不用逗号均可),也可用于句中表强调。而despite多用于句中和句首。
扩展资料
一、although
英 [ɔ:lˈðəu] 美 [ɔlˈðo]
conj.虽然;尽管;但是;然而
例句
1、Although the shooting has stopped for now, the destruction left behind is enormous.
虽然枪战目前已停止，但造成的破坏是巨大的。
2、Although he was twice as old as us, he became the life and soul of the company.
虽然他的年纪是我们的两倍，但他却成为了公司的灵魂人物。
3、Although not ideal, this attitude is not entirely destructive.
这种态度虽然不够理想，但还不至于消极透顶。
二、despite
英 [dɪˈspaɪt] 美 [dɪˈspaɪt]
prep.不管;虽有;尽管（自己）不愿意;不在乎
n.侮辱;憎恨;怨恨
例句
1、Despite winning the title, their last campaign ended in greatdisappointment
尽管赢得了冠军，但他们最后一役却令人大失所望。
2、Mr Lawssi apparently did not return the money, despite repeatedreminders
尽管被提醒了很多次，劳西先生显然没有把钱退回来。
3、Despite myself, Harry's remarks had caused me to stop and reflect.
哈里的话让我不由自主地停下来细想。