though和however的区别为：意思不同、用法不同、侧重点不同。
一、意思不同
1.though意思：虽然;尽管;即使;(用于主句后，引出补充说明，使语气变弱)不过
2.however意思：(与形容词或副词连用)无论到什么程度，不管多么;不管怎样;无论如何
二、用法不同
1.though用法：though引导让步状语从句时表示一种假设的情况或含有推测的意味，从句的谓语动词可用陈述式，也可用虚拟式，有时为了强调让步的意义，可采用倒装语序。
2.however用法：however 通常引导一个让步状语从句，从句中的形容词或副词必须紧接其后。however多插在句中，有时也放在句首或句尾，但都应紧跟在进行对比的词或短语之后，用逗号将其与其他词分开。
三、侧重点不同
1.though侧重点：though在非正式语体中较为普遍， though可以用在倒装句中。
2.however侧重点：however并不直接引出相反的意见，因此常用作插入语。
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第1个回答 2013-09-16
首先，二者的意思就不同。though是“虽然”的意思，however是“但是”的意思。带有though的句子不能与but连用。However能放句首或者句中，后要接逗号。
第2个回答 推荐于2018-02-25
though
1.虽然;尽管
Though he is rich, his life is not happy.
他虽然很有钱,但生活并不幸福。
2. (一般放在句尾)然而,还是
It was a hard job, he took it though.
这是份苦差事,可他还是接受了。
however
1. 然而,可是,不过
I feel a bit tired. However, I can hold on.
我有点累了,但我能坚持下去。
2.无论如何,不管怎样
However hot it is, he will not take off his coat.
无论多热,他也不会脱掉外衣。
3. 不管用什么方法
However he tries, he never seems able to work satisfactorily.
不管他怎么努力,他好像总不能令人满意地工作。
4. 究竟怎样,到底如何
However did you know that?
你到底怎么知道那件事的?
however后+句子，要用，隔开；though不用本回答被网友采纳
1.虽然;尽管
Though he is rich, his life is not happy.
他虽然很有钱,但生活并不幸福。
2. (一般放在句尾)然而,还是
It was a hard job, he took it though.
这是份苦差事,可他还是接受了。
however
1. 然而,可是,不过
I feel a bit tired. However, I can hold on.
我有点累了,但我能坚持下去。
2.无论如何,不管怎样
However hot it is, he will not take off his coat.
无论多热,他也不会脱掉外衣。
3. 不管用什么方法
However he tries, he never seems able to work satisfactorily.
不管他怎么努力,他好像总不能令人满意地工作。
4. 究竟怎样,到底如何
However did you know that?
你到底怎么知道那件事的?
however后+句子，要用，隔开；though不用本回答被网友采纳
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